Page 95 - Clinical relevance of current materials for cranial implants

In vivo fractured PMMA cranioplasty
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Figure 5: A and B) Representative gel permeation chromatography curves of the fractured PMMA cranioplasty, C and D) CMW-3. A and C depict the results from the ultraviolet/visible photodiode array detector at 254 nm, B and D depict the results from the refractive index detector.
Table 2: Representative gel permeation chromatography results of the implant and reference samples, Mn, Mw, and Mz data, in g/mol, are relative to polystyrene standards.
Material
Implant
CMW-3
Porosity
Sample # Mn
1 90,138 2 96,789 3 87,441 4 87,706 1 88,232 2 95,322
Mw Mz PDI
238,850 488,988 2.65 245,156 504,793 2.53 218,874 404,050 2.50 241,354 487,383 2.75 234,735 471,701 2.66 245,214 491,876 2.57
The density of the fractured cranioplasty was 1.147 g/cm3, while the densities of CMW- 3 were 1.156 (cured at atmospheric pressure) and 1.246 g/cm3 (cured at 2.2 bar). This results in a macroscopic porosity of 7.9% for the fractured cranioplasty and 7.3% for CMW-3 cured at atmospheric pressure. The μCT of the fractured cranioplasty showed a total porosity of 10.7%. The specimen of the CMW-3 cured at atmospheric pressure had a porosity of 4.1% and the specimen of CMW-3 cured at 2.2 bar had a porosity of 0.06%. (Figure 6)
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