Page 94 - Clinical relevance of current materials for cranial implants
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Chapter 4
Statistical analysis
The flexural strength data were statistically analyzed using one-way analysis of variance (ANOVA) followed by Tukey’s post hoc test (α = 0.05) in SPSS version 24.0 (IBM, Armonk, NY, USA). Student’s t-test was used to analyze the GPC data.
RESULTS
In this ex vivo study a CMW-3 PMMA fractured cranioplasty, which was part of the patient’s cranium for 15 years, was compared to fresh specimens of CMW-3 cured at 2.2 bar and at atmospheric pressure. To determine whether the chemical, structural, and mechanical properties of CMW-3 change over time GPC, μCT, and flexural strength tests were performed. The fracture itself was analyzed using FEA.
Gel permeation chromatography
All samples were analyzed using RI detection since PMMA does not contain chromophores; the UV/Vis-PDA detector therefore, did not produce useful data (Figure 5). The number average molecular weight (Mn), weight average molecular weight (Mw), Z average molecular weight (Mz), and polydispersity index (PDI) are comparable for each group respectively (Table 2).The PDI was not significantly different for the fractured implant and CMW-3 (p = 0.94). No significant difference in Mn (p = 0.76), Mw (p = 0.70), or Mz (p = 0.78) was detected between the implanted material and CMW-3.
