Page 169 - Fluorescence-guided cancer surgery

Clinical translation of OTL38 in ovarian cancer 167
Table 1. Surgery and tumor characteristics of ovarian cancer patients
Patient ID
Surgical procedure
Diagnosis
FIGO stage Grade
Metastases Tumor FRα identi ed positive
Fluorescence imaging successful
1 2 3 4 5 6 7
Interval debulking
Serous adenocarcinoma Serous adenocarcinoma Serous adenocarcinoma Serous adenocarcinoma Serous adenocarcinoma Mucinous adenocarcinoma Endometrioid carcinoma
4 III 4 III 3c III 4 III 3c III
Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
Yes Yes Yes Yes Yes Yes Yes
8 9
Primary debulking
Serous adenocarcinoma Clear cell carcinoma
3c III 3 I
Yes Yes Yes Yes
Yes Yes
10 11
Interval debulking
Mucinous adenocarcinoma Endometrioid carcinoma
3c Unknown
Yes Yes
Yes Yes
12
Interval debulking
Adenocarcinoma† 3c
Yes
Interval debulking
Interval debulking
Interval debulking
Interval debulking
Primary debulking
3b Unknown 3b II
Debulking recurrent disease
Debulking recurrent disease
Debulking recurrent disease
3c
III Yes III Yes
Yes Yes
FIGO, International Federation of Gynecology and Obstetrics; FRα, folate receptor alpha † Further classi cation was not possible due to prior chemotherapy