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Chapter 8158Some studies have described female patients experiencing better improvement in self-esteem and a greater reduction in depression after orthognathic surgery compared to male patients.3,31,32 Corso et al. found, in both the dentofacial deformities group and control group, a lower perception of QoL by women compared to men. However, some studies did not find a difference in OHIP core between men and women.31,32,35 The present study also found no difference in OHIP score between men and women. This study found no difference in regards to the type of surgery. However, some investigators have found better improvement in patients who underwent BIMAX compared to single jaw surgery (Le Fort I or BSSO).29 Another study evaluated whether a combination of BIMAX and genioplasty for females with prognathism and maxillary hypoplasia has a greater positive impact on QoL than BIMAX alone; genioplasty led to significantly greater QoL after surgery.36The current study did not find a significant difference between indications for surgery. Some other studies also found no significant association between the indication for surgery and OHIP-14 scores.28,35 However, other studies have found that skeletal class III patients had more positive effects form surgery than class I and class II patients.29,32 Baherimoghaddam et al. found an improvement in both class II and class III patients, but the pattern of change was different; class II patients experience deterioration in QoL during the preoperative stage and improvement in function rather late in the postoperative stage. Class III patients exhibited more significant changes in the domains concerning appearance and psychological issues.34 Another finding in this study was that the OHIP score for every question was significantly lower at least 1 year after the operation compared to baseline, except for question 14, which refers to total oral dysfunction. The fact that the OHIP score for question 14 was only 0.4 at baseline indicates that people with various dentofacial deformities do not or hardly suffer from total oral dysfunction. This could explain why no improvement was noted after 1 year. The patients recruited for this study may have more problems with their facial appearance psychologically than with function.