Page 19 - scheppingen
P. 19
Dysmorphic neuron
TLR4, NKCC1 RAGE, IL-1R, iGluRs Group I mGluR
Glu transporters Ion channels, KCC2 GABAAR subunits
TLR2 RAGE IL-1R1
Reactive astrocyte
Microglia
Endothelium
GENERAL INTRODUCTION & OUTLINE OF THE THESIS
mTOR overactivation early in development
Giant cell
Epileptogenesis
Enhanced excitability
Chronic epilepsy
pharmacoresistance and comorbidities
TLR2 RAGE IL-1R1
Change in BBB permeability
TLR4
RAGE
IL-1R
Glu transporters Ion channels KCC2
one
17
