Page 122 - Magnesium-based supports for stem cell therapy of vascular disease - Mónica Echeverry Rendón

CHAPTER 7
Fig.6. followed up of changes in the monolayer after addition of the Mg extracts. After 6h cells treated with HMT and MAN present similar behavior as the control while cells treated with c.p Mg after the 3 h died.
These results highlight the protective effect of the Mg-coatings and its contribution to decrease the rate of release of Mg ions. Moreover, no significant differences in -logEC50 or Emax were found between the four groups (Fig.7), implying that the remaining ECs where similarly responsive to Bradykinin.
Fig.7. Endothelium dependent relaxation. Right coronary arteries from pigs were incubated with Mg extracts and its dependent relaxation mediated by Bradykinin was studied. Rings treated with c.p Mg showed a decrease in the % of constriction whereas that rings treated with HMT and MAN extracts showed no significant differences with the control.
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