Page 21 - Human Bile Acid Metabolism: a Postprandial Perspective

in the biology of bile acids and their receptors in different cells and tissues. While 1 preclinical studies show promising effects, clinical studies are scarce. We give a
summary of key concepts in bile acid metabolism; outline different downstream
effects of TGR5 activation; and review available data on TGR5 activation, with a
focus on the translation of preclinical studies into clinically applicable findings.
Introduction
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