Page 116 - Demo

Chapter 5114A. Intellectual disabilityGenetic neurodevelopmental disordersNeurometabolic disordersB. PROs ClinROs ObsROs PerfOsDomains of interestFigure 1. A) Schematic representation of target populations. Importantly, it represents an indication rather than a precise scaled proportion of target populations. B) Types of clinical outcome assessments (upper) and domains of interest to this review (lower; blue boxes: symptom and functional status related to neurological functioning, and the overarching concepts of perceived health and overall quality of life). This is based on the conceptual model of health outcomes from Valderas & Alonso which incorporates both the commonly used models of the ICF and Wilson & Cleary.3,31 Figure adapted from Valderas & Alonso.ClinRO, clinician-reported outcome; ICF, International Classification of Functioning, disability and health; ObsRO, observer-reported outcome; PerfO, performance outcome; PRO, patient-reported outcome.Annelieke Muller sHL.indd 114 14-11-2023 09:07