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Chapter 4108907) and abstract (n = 119). By reading the final 52 articles and applying the inclusion criteria, a total of 13 articles were analyzed. Two additional articles were identified by manually searching the reference list of one of the meta-analyses. The performed search is summarized in the PRISMA flow diagram (Fig. 1). Five articles met the inclusion criteria for stock prostheses(3,16,19–21), while eight were included for patient-specific TMJ TJR.(11–15,22–24) Both Machon et al.(25) and Gonzalez-Perez et al.(17) evaluated both a stock system and PSI. The basic characteristics of the included articles are in Tables 2 to 5. As stated earlier, not all articles that were included in the systematic review were included in the metaanalysis, as to prevent duplication of patient population. In total, 12 of the 15 included articles provided data that were included in the meta-analysis.(3,13,24,25,14–16,19–23) A total of 413 patients were treated with either a uni- or bilateral patient-matched implant, while 691 patients were treated with a stock implant. While not all articles reported on sex, a clear female dominance with 411 female patients versus 220 male patients for stock implants.(3,20,21,25) This was more so the case for the PSI, with 308 and 36 female and male patients, respectively.(13,15,23–25) Both groups were also relatively similar in age. A more detailed overview of the study populations for stock and custom(ized) TMJ TJR can be found in Tables 2 and 3.We chose not to divide the included prosthetic systems on basis of brand for this meta-analysis. As a result, a direct comparison was made between both stock and patient-fitted systems. While not intentional, all stock TMJ TJRs consisted of the Biomet system, with less heterogeneity in the PSI group.Risk of biasAll 15 studies were assessed using the MINORS scale. Only those by Machon et al.(25) and Gonzalez-Perez et al.(17) were of comparative nature. Overall, the risk of bias was relatively low for articles dealing with stock and custom(ized) systems, with respective mean scores of 12/16 and 12.2/16 for the non-comparative articles. It should be noted that all included articles either did not report on or did not prospectively calculate Nikolas de Meurechy NW.indd 108 10-06-2024 11:04