Page 71 - New epidemiological and PSMA-expression based paradigms in salivary gland tumors
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Malignant transformation of pleomorphic adenoma: Proof of principle
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Figure S2. NGS analysis of TP53 and PIL3R1 mutations in the primary tumor and the first and second recurrences showing that (A) the first recurrence harboured a TP53 p.R248Q; c.743G>A mutation in exon 7 (VAF: 46%). (B) In the second recurrence a different TP53 mutation was present in exon 6: TP53 p.Y220C; c.659A>G (VAF: 51%). Both mutations were absent in the primary tumor. (C) The PIK3R1 mutation was present in the primary tumor, and both the first and second recurrences.
