Page 127 - Migraine, the heart and the brain
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 Cerebellar function and ischemic brain lesions in migraine
Figure 3. Eyeblink conditioning in non-migraine controls, migraine patients with or without aura, and patients with FHM1. (a) Experimental paradigm for the eyeblink conditioning task. The unconditioned stimulus (US) was a mild air puff (30 ms), which was applied to the left eye and elicited a reflexive eyeblink. The conditioned stimulus (CS) was a clearly audible tone (1 kHz, 70–80 dB, duration 580 ms), presented via headphones. Each training session consisted of eight blocks, separated by an inter-block interval (IBI) of 120 ± 20 s. Each block in turn consisted of eight trials separated by an inter-trial interval (ITI) of 30 ± 10 s. CS and US were presented in a delay paradigm, in which the interval between CSand US-onset was 550 ms. (b) Analysis of raw data traces. Eyelid
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