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Chapter 2
Appendix 8 Baseline characteristics of participants with T1N0 OPC. P values shown for comparisons between groups.
aChi-square test, bindependent samples t-test. Percentages and statistical tests
for available cases only.
   Intended treatment
Number of participants (%)
  P value Surgery vs. RT
  Intended and received treatment
Number of participants (%)
 P value Surgery vs. RT
    Surgery (n = 39)
  RT
(n = 25)
   Surgery (n = 31)
  RT
(n = 24)
   Gender Male Female
Age at diagnosis (years)
26 (67) 13 (33)
60 (11)
9 (24)
11 (29) 7 (18) 7 (18) 4 (11) 1
2 (7) 15 (56) 10 (37) 12
7 (26) 6 (22) 9 (33) 5 (19) 12
12 (33) 16 (44) 8 (22) 0 (0)
3
1 (3)
9 (23) 29 (74)
20 (77) 6 (23) 13
31 (80)
1 (3) 0 (0) 7 (18) 0 (0)
18 (69) 8 (31)
13
15 (60) 10 (40)
61 (7)
4 (17)
8 (33) 4 (17) 6 (25) 2 (8) 1
3 (53) 4 (27) 8 (20) 10
3 (18) 2 (12) 7 (41) 5 (29) 8
9 (36) 13 (52) 2 (8)
1 (4)
0
0 (0)
9 (36) 16 (64)
17 (77) 5 (23) 3
0 (0)
24 (96) 0 (0)
1 (4)
0 (0)
15 (88) 2 (12)
8
.588a
.696b
.933a
.160a
.645a
.325a
.411a
.977a
NA
.149a
19 (61) 12 (39)
61 (12)
7 (23)
9 (30) 4 (13) 7 (23) 3 (10) 7 (23)
2 (9) 11 (48) 10 (44) 8
7 (30) 3 (13) 8 (35) 5 (22) 8
10 (35) 12 (41) 7 (24) 0 (0)
2
1 (3)
6 (19) 24 (77)
18 (86) 3 (14) 10
31 (100)
0 (0) 0 (0) 0 (0) 0 (0)
16 (73) 6 (27)
9
14 (58) 10 (41)
61 (7)
4 (17)
8 (35) 4 (17) 5 (22) 2 (9) 4 (17)
2 (14) 4 (29) 8 (57) 10
3 (19) 1 (6) 7 (44) 5 (31) 8
8 (33) 13 (54) 2 (8)
1 (4)
0
0 (0)
8 (33) 16 (67)
17 (81) 4 (19) 3
0 (0)
24 (100) 0 (0)
0 (0)
0 (0)
14 (88) 2 (13)
8
.824a
.849b
.974a
.501a
.692a
.308a
.363a
.679a
NA
.270a
  Mean (SD)
Deprivation index
Smoking
Alcohol
ACE-27
Oropharyngeal tumour site
HPV status
Received treatment
Pre-treatment swallowing problems
1 (most deprived)
2
3
4
5 (most affluent) Unknown
Never used Former user Current user Unknown
Non-drinker Moderate Hazardous Harmful Unknown
None Mild Moderate Severe Unknown
Base of tongue Tonsil
Other
Negative Positive Unknown
Surgery
RT
CRT
Surgery + (C)RT No treatment
No Yes
Unknown
                 50
NB: Not all percentages sum up exactly to 100% due to rounding.
Abbreviations: ACE-27 = Adult Comorbidity Evaluation-27, HPV = human papilloma virus, SD = standard deviation.
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