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Chapter 2
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Appendix 7 Self-reported swallowing outcomes and secondary functional outcomes at 4- and 12-month follow-up grouped by intended and received surgery (with or without adjuvant (C)RT) and RT only. Poisson regression analysis comparing RT to surgery (reference).
Self-reported swallowing outcomes (from EORTC-QLQ-H&N35)
Problems swallowing liquids, pureed or solid food
No 32 (84) Yes 6 (16) Unknown 28
No 36 (95) Yes 2 (5) Unknown 28
34 (44) 44 (56) 48
67 (85) 12 (15) 47
21 (49)
22 (51)
35
35 (80) 9 (21) 34
MA: 4.1 (1.4–12.1) A: 3.2 (1.3–8.2)
.011 .013
30 (88) 4 (12) 32
34 (100) 0 (0)
41 (61) 26 (39) 59
63 (93) 5 (7) 58
33 (70) 14 (30) 31
43 (92) 4 (9) 31
MA: 2.9 (0.9–8.8) A: 2.7 (1.1–6.7)
.067 .027
Problems swallowing liquids
NA
NA NA
Problems swallowing pureed food
No 34 (90) Yes 4 (11) Unknown 28
No 32 (87) Yes 5 (14) Unknown 29
58 (76) 18 (24) 50
35 (44) 44 (56) 47
34 (79) 9 (21) 35
21 (50) 21 (50) 36
MA: 4.8 (0.7–32.0) A: 2.7 (0.4–17.8)
.109 .296
32
34 (100) 0 (0)
32
30 (88) 4 (12) 32
60 (90) 7 (10) 59
42 (62) 26 (38) 58
44 (94) 3 (6) 31
34 (72) 13 (28) 31
Problems swallowing solid food
MA: 4.1 (1.4–12.1) A: 3.2 (1.3–8.2)
.011 .013
MA: 2.8 (0.9–8.6) A: 2.7 (1.7–6.7)
.072 .027
Secondary functional outcomes (from EORTC-QLQ-H&N35)
Weight loss
No 30 (79) Yes 8 (21) Unknown 28
No 37 (97) Yes 1 (3) Unknown 28
32 (41) 46 (59) 48
65 (81) 15 (19) 46
24 (55) 20 (45) 34
35 (76) 11 (24) 32
MA: 2.9 (1.3–6.4) A: 2.7 (1.2–6.0)
.009 .018
29 (85) 5 (15) 32
34 (100) 0 (0)
42 (66) 22 (34) 62
64 (96) 3 (4) 59
36 (80) 9 (20) 33
44 (94) 3 (6) 31
MA: 2.4 (0.9–6.2) A: 2.8 (0.9–8.5)
.065 .077
Tube feeding
NA
NA
Pain mouth, jaw or throat
No 28 (74) Yes 10 (26) Unknown 28
47 (60) 32 (41) 47
21 (49) 22 (51) 35
MA: 2.2 (0.9–5.6) A: 2.0 (0.9–4.6)
.097 .105
32
26 (79) 7 (21) 33
51 (76) 16 (24) 59
34 (77) 10 (23) 34
MA: 1.4 (0.5–3.9) A: 2.3 (0.6–8.2)
.558 .211
4-month follow-up
12-month follow-up
Number of participants (%)
Regression analysis
Number of participants (%)
Regression analysis
Surgery RT Surgery and
(n = 66) (n = 126) received surgery + (C)RT (n = 78)
RR (95% CI)
P value
Surgery (n = 66)
RT
(n = 126)
Surgery and received surgery + (C)RT (n = 78)
RR (95% CI)
P value
