Page 127 - Functional impairment and cues for rehabilitation of head and neck cancer patients -

Functional outcomes after (C)RT for OPC
Figure 5 Percentage of patients with a modified diet (FOIS < 7) (a), trismus (b) or speech problems (vowel space area < 80%) (c) at t0, t1 and t2 stratified by HPV status.
Sarcopenia
Appendix 11 shows the baseline characteristics stratified by pretreatment sarcopenia. Patients with pretreatment sarcopenia were more often female, had a lower BMI, higher T-classifications, higher disease stages, more often an HPV negative tumor, and more often had a modified diet at baseline compared to patients without pretreatment sarcopenia.
All outcomes stratified by pretreatment sarcopenia are presented in Figure 6 and Appendix 12. As presented in Figure 6a, pretreatment sarcopenia was associated with more modified diet at all timepoints. Also, at t0 and t1, SWAL-QOL scores were higher in patients with sarcopenia, indicating more swallowing related problems. At t2, SWAL-QOL scores were comparable. Trismus outcomes were comparable between patients with and without sarcopenia at t0, t1 and t2. Prevalence of objective speech problems (vowel space area below 80%) was comparable at t0 and t1, but higher in patients with sarcopenia at t2. Patient reported speech problems, however, were more prevalent in patients with sarcopenia. After adjusting for AJCC stage and pretreatment modified diet, only modified diet and the total SWAL-QOL score at t1 were significantly higher in patients with pretreatment sarcopenia.
5
125