Page 122 - Organ motion in children for high-precision radiotherapy - Sophie Huijskens

7.2 | Methods
Patient data
From November 2014 to December 2017, fourteen patients (mean age 14.5 years, range 8.6-17.9 years) had a 4DCT scan during free breathing for treatment planning purposes and multiple CBCT scans acquired for position verification during the treatment course. Patients were included when the complete diaphragm was visible on the 4DCT and CBCTs. Two of the fourteen eligible patients were excluded from this retrospective study; one patient received general anesthesia (GA) and the imaging data of another patient showed severe motion artefacts. Patient characteristics are listed in Table 7.1.
Table 7.1 | Patient characteristics
No. Sex
1 M
2 F
3a F 4a M 5b F 6b M 7b M
8 M
9 F
10 F
11b M 12 M
Tumor type
Ewingsarcoma Ewingsarcoma Ewingsarcoma Osteosarcoma Ewingsarcoma ERMS Ewingsarcoma CCS
Non Hodgkin Ewingsarcoma RMS prostate Non-RMS
Age at 4DCT (years)
10.7
16.3
17.9 14.9 12.5 16.1 14.3 8.6 17.1 14.8 16.7 14.4
Height (cm)
137
162
163
186
151
182
182
125
178
153
186
172
Weight (kg)
28.0
66.5
52.6
71.6
70.0
57.6
55.6
23.0
86.0
57.0
64.0
59.0 12
No. of CBCTs
7
8
12
5
29
19
6
5
11
7
4
Abbreviations: M = male; F = female; 4DCT = four-dimensional computed tomography; CBCT = cone beam CT; (E)RMS = embryonal rhabdomyosarcoma; CCS = clear cell sarcoma
a Patients had within multiple treatment sessions repetitive CBCTs (only the 1st and 2nd were included in the analysis)
b Patients had two CBCTs within one treatment session
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