Page 95 - Effects and Efficacy of (Laparoscopic) Gastrostomy Placement in Children - Josephine Franken
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Appendix 2B. 24-hour Mii-pH monitoring: patients without preoperative pathological reflux (n=7).
Chapter 5
Preoperative Postoperative Mean difference median (iQR) median (iQR) (95% Ci)1
i. pH analysis
Total acid exposure per 24 hour (%) 1.3 (0.6 – 2.6) 2.5 (1.6 – 7.5) 1.9 (0.1 – 3.8)
supine position (0.6 (0.3 – 0.8) 2.2 (0.1 – 6.3) 3.2 (-1.5 – 8.0)
Upright position 0.6 (0.2 – 5.7) 1.9 (1.0 – 4.1) 2.3 (-3.9 – 8.6)
number of reflux episodes (pH<4) 11.6 (6.1 – 41.2) 17.0 (8.5 – 19.2) -7.0 (-26.2 – 12.2)
number of episodes > 5 min. 0.0 (0.0 – 1.2) 1.3 (1.1 – 2.2) 1.3 (0.2 – 2.4)
Longest reflux episode (min.) 3.7 (2.2 – 5.7) 18.9 (6.0 – 26.2) 19.6 (-4.0 – 43.1)
Lowest pH 0.9 (0.4 – 1.4) 0.9 (0.8 – 1.1) -0.2 (-1.3 – 0.9)
ii. impedance analysis
Total reflux episodes per 24 hour 31.6 (23.6 – 38.8) 25.6 (17.9 – 38.2) -4.3 (-21.0 – 12.3)
Acid 18.2 (4.1 – 25.0) 10.2 (8.1 – 21.5) -3.8 (-14.1 – 6.4)
Weakly acidic 13.5 (6.2 – 27.5) 7.9 (5.7 – 17.1) -0.3 (-8.8 – 8.2)
Liquid reflux 16.2 (13.7 – 19.4) 11.8 (7.9 – 21.0) -1.3 (-9.7 – 7.1)
Acid 8.0 (1.0 – 15.0) 6.1 (3.2 – 9.0) -1.9 (-7.1 – 3.3)
Weakly acidic 5.7 (2.1 – 14.2) 4.5 (3.9 – 8.5) 0.5 (-3.9 – 4.9)
Mixed reflux 15.0 (6.4 – 19.4) 13.9 (9.1 – 17.3) -2.7 (-12.2 – 6.7)
Acid 6.4 (3.1 – 10.3) 5.7 (4.5 – 9.9) -1.9 (-7.5 – 3.6)
Weakly acidic 8.0 (1.2 – 11.2) 4.5 (3.4 – 8.5) -0.8 (-5.6 – 4.1)
Proximal extend
Z1 (proximal esophagus) 19.0 (0.0 – 50.0) 17.0 (13.0 – 38.0) 0.71 (-23.1 – 24.5)
Z3 (mid esophagus) 55.0 (39.0 – 80.0) 74.0 (63.0 – 75.0) 12.3 (-4.7 – 29.2)
Z5 (distal esophagus) 100 (100 – 100) 100 (100 – 100) NA
BCT in Z6 (sec.) 17.8 (9.2 – 28.0) 12.1 (10.7 – 18.9) 3.5 (-14.3 – 21.2)
Upright 18.2 (17.3 – 34.1) 11.5 (10.3 – 20.9) 0.03 (-19.4 – 19.4)
supine 13.2 (7.3 – 28.1) 13.4 (9.1 – 22.9) -1.4 (-20.0 – 17.3)
Legend: 1. Paired samples t-test was used when differences were normally distributed. BCT = bolus clearance time; GER = gastroesophageal reflux; IQR = interquartile range; NA = not applicable; 95% CI = 95% confidence interval.
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