Page 94 - Effects and Efficacy of (Laparoscopic) Gastrostomy Placement in Children - Josephine Franken
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Appendix 2A. 24-hour Mii-pH monitoring: patients with preoperative pathological reflux (n=18).
Preoperative Postoperative Mean difference median (iQR) median (iQR) (95% Ci)1
i. pH analysis
Total acid exposure per 24 hour (%) 10.8 (5.7 – 23.1) 8.8 (3.5 – 21.7) -1.1 (-8.3 – 6.1)
supine position 13.3 (4.5 – 24.8) 6.1 (3.1 -19.8) -3.1 (-9.9 – 3.6)
Upright position 11.3 (3.5 – 20.6) 9.9 (1.5 – 14.6) -1.4 (-6.5 – 3.7)
number of reflux episodes (pH<4) 59.9 (49.8 – 78.3) 50.0 (31.5 – 72.7) -16.1 (-49.8 – 17.6)
number of episodes > 5 min. 5.4 (1.5 – 25.4) 4.1 (1.2 – 11.2) -2.0 (-5.4 – 1.4)
Longest reflux episode (min.) 33.0 (7.3 – 52.5) 17.4 (7.9 – 29.1) -12.5 (-30.8 – 5.8)
Lowest pH 0.6 (0.5 – 1.0) 0.8 (0.5 – 1.0) 0.1 (-0.2 – 0.3)
ii. impedance analysis
Total reflux episodes per 24 hour 73.1 (49.4 – 83.5) 75.5 (47.6 – 127.7) 14.8 (-14.1 – 43.7)
Acid 53.8 (43.3 – 70.2) 54.5 (30.6 – 74.1) 5.4 (-20.0 – 30.8)
Weakly acidic 18.1 (8.8 – 24.7) 25.1 (8.6 – 35.0) 8.0 (-1.5 – 17.6)
Liquid reflux 38.0 (28.3 – 51.2) 43.1 (32.0 – 56.0) 6.7 (-6.3 – 19.8)
Acid 28.6 (15.5 – 40.0) 23.8 (13.2 – 38.3) 4.2 (-9.8 – 18.1)
Weakly acidic 8.6 (6.4 – 20.2) 13.0 (7.1 – 23.5) 2.6 (-1.5 – 6.7)
Mixed reflux 28.0 (19.7 – 43.1) 35.2 (20.2 – 43.7) 4.6 (-12.2 – 21.4)
Acid 20.9 (16.3 – 36.9) 26.7 (8.8 – 36.2) 1.2 (-13.3 – 15.6)
Weakly acidic 6.0 (2.6 – 10.6) 10.0 (1.2 – 16.6) 4.7 (-2.5 – 12.0)
Proximal extend
Z1 (proximal esophagus) 31.0 (12.5 – 35.0) 22.0 (16.5 – 37.0) 1.9 (-8.2 – 12.1)
Z3 (mid esophagus) 71.0 (64.5 – 83.0) 75.0 (57.5 – 87.0) 1.1 (-7.9 – 10.2)
Z5 (distal esophagus) 100 (100 – 100) 100 (100 – 100) NA
BCT in Z6 (sec.) 16.8 (13.8 – 20.5) 15.7 (14.5 – 17.7) -1.3 (-5.7 – 3.1)
Upright 15.9 (13.7 – 17.9) 14.2 (11.7 – 18.4) -0.7 (-3.9 – 2.5)
supine 16.0 (12.1 – 22.1) 16.3 (10.3 – 21.5) 1.6 (-5.4 – 8.7)
Legend: 1. Paired samples t-test was used when differences were normally distributed. BCT = bolus clearance time; GER = gastroesophageal reflux; IQR = interquartile range; NA = not applicable; 95% CI = 95% confidence interval.
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