Page 108 - Postoperative Intra-Abdominal Adhesions- New insights in prevention and consequences

Chapter 6
Figure 3. Percentage of the mesh edge incorporated into the abdominal wall. At 30 days, no significant differences were found. Values are median (interquartile range). §p < 0.050 versus Prolene, Strattice, and Permacol. For each mesh, no significant differences were observed between 30 and 90 days (Mann–Whitney U test).
Shrinkage
At 30 days Surgisis showed significantly more shrinkage than any of the other meshes (39%, IQR 37.1-50.6%). More shrinkage occurred with both Permacol (13.7%, IQR 8.6-22.6%) and Strattice (16% IQR 14.3- 19.2%) than with Parietex Composite. No significant differences were seen between Prolene (11%, IQR 8.6-16.2%) and Parietex Composite (9%, IQR 5.7-13.6%). At 90 days Surgisis resulted in significant more shrinkage than any of the other meshes (65%, IQR 42.4-74.3%) (Fig 4). The percentage of shrinkage shown by Strattice (28%, IQR 22.9-28.0%) was significantly higher than that shown by Prolene (16%, IQR 11.4- 18.5%). After 90 days, Parietex Composite demonstrated shrinkage of 23% (IQR 9.7-31.7%) and Permacol exhibited 17.7% (IQR 12.2-23.8%). All the meshes except Prolene and Permacol showed significantly more shrinkage at 90 days than at 30 days.
Tenacity of adhesions
At 30 days the Zühlke score for adhesions to the Permacol mesh was significantly higher than the score for Prolene (p=0.011), Parietex Composite (p=0.004) and Surgisis (p=0.007). Organs were attached
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