Page 50 - Reconstructive Techniques in Musculoskeletal Tumor Surgery

Chapter 2
48
Table 5. continued
Reference
Years of surgery
Patients
Chondrosarcoma subtypes
Follow-up
Primary Clear hindquarter margins amputation
Recurrence
Metastasis
Infection
Limb salvage at time of follow-up
Risk factors for impaired survival
Notes
Deloin
1968 - 2003
59
Primary (n=47), secondary (n=9) and multiple (n=3)
Survivors: mean 10.3 (4.0-22.7) Deceased: mean 5.6 (0.3-26.0)
19% 81%
31%
20%
10%
75%
Resection margins, tumor grade, acetabular involvement
-
Ozaki Pring
1970 - 1993
31 64
Primary (n=23) and secondary (n=8)
Median 5.0 years (0.3-22.3)
26% Wide margins:
45% 19%
6% 17%
16% 13%
61% 80%
Tumor grade
Resection margin correlated with local recurrence rate.
Wirbel
1978 - 1998
51 162
N/R
Mean 6.1 (0.3-19.1)
25% 84% 17% 77%
20% 38%
35% 30%
20% 19%
69% 75%
Tumor stage, resection margin
Two perioperative deaths.
Current study
1985 - 2013
Conventional primary central
Survivors: median 9.2 (2.0-27.5) Deceased: median 3.0 (0.1-15.1)
Tumor grade, resection margins, tumor size, soft-tissue in ltration
-
1975 - 1996
Primary (n=49) or secondary (n=15); conventional (n=57) and dedi erentiated (n=7)
Survivors: median 11.7 (3.3-24.6)
26% 20% 83%
Tumor grade, tumor stage and having a primary lesion.
Curettage in 5%. Resection margin correlated with local recurrence rate.