Page 49 - Reconstructive Techniques in Musculoskeletal Tumor Surgery

Pelvic chondrosarcoma
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Table 5. Overview of literature on pelvic chondrosarcoma.
Reference
Years of surgery
Patients
Chondrosarcoma subtypes
Follow-up
Primary hindquarter amputation
Clear margins
Recurrence
Metastasis
Infection
Limb salvage at time of follow-up
Risk factors for impaired survival
Notes
Donati
1971 - 1999
124
Conventional central (51%) and peripheral (49%)
N/R
24%
Wide margins: 73% of central and 57% of peripheral tumors
18%
8%
N/R
N/R
Tumor grade, internal hemipelvectomy
Curettage in 1%. No relationship between grade and LR rate (but higher rate of ablative surgery for grade 3 lesions). Central lesions had worse long-term survival (73% at follow- up).
Guo
1997 - 2006
45
Conventional (71%), dedi erentiated (20%), mesenchymal (9%); all involving the periacetabulum
Survivors: mean 3.1 (1.5-9.9) Deceased: mean 3.6 (0.6-5.9)
13%
84%
22%
22%
11%
N/R
-
29% of the patients were initially treated elsewhere. No association between obtained margins and the occurrence of metastases.
Mavrogenis
1975 - 2008
215
Primary or secondary conventional central (55%), peripheral (40%), not speci ed (4%), periosteal (1%)
Mean 8.6 (2-31)
19%
84%
30%
14%
(of the patients without metastases at diagnosis)
N/R
N/R
Tumor grade
Curettage in 3%. Tumor grade was the most important prognostic factor. Patients with a periacetabular lesion had worse survival.
Mochizuki
1989 - 1998
135
N/R
Mean 3.9 (0.3-10.0)
10%
79%
24%
19%
19%
N/R
Tumor stage, site, size and achieved margins
Patients included from 58 institutions.
Sheth
1970 - 1992
67
Primary or secondary conventional (81%) and dedi erentiated (19%)
Survivors: median 9.6 (2.0-24.0) Deceased: median 0.9 (0.0-10.3)
52%
57%
28%
36%
N/R
N/R
Tumor grade
Inadequate margins, tumor epicenter in the pubis, and tumor grade were associated with an increased risk of local recurrence.