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                                SYSTEMATIC REVIEW
         II
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Table 1. Characteristics of the 22 included studies. SUR: patients treated with surgery. RTC: patients treated with radiotherapy or conservative therapy. NR: not reported
Study ID
Author, year, country
Study type
No. patients
% SUR/RTC
Follow-up
Period recruitment
Duration recruitment
Risk of Bias
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Helweg, 2000, Denmark Riegel, 2002, Germany Linden, 2004, Netherlands Hosono, 2005, Japan Ibrahim, 2008, International Chi, 2009, USA Arrigo, 2011, USA Bartels, 2011, International Mizumoto, 2011, Japan Park, 2011, Korea Pointillart, 2011, France Wibmer, 2011, Austria Chao, 2012, USA Kataoka, 2012, Japan Tancioni, 2012, Italy Yang, 2012, Korea Balain, 2013, UK Rades, 2013, Germany Tabouret, 2013, France Bollen, 2014, Netherlands Morgen, 2014, Denmark Yeung, 2014, Hong Kong
Prospective Retrospective Prospective Retrospective Prospective Prospective Retrospective Retrospective Retrospective Retrospective Prospective Retrospective Retrospective Retrospective Retrospective Retrospective Prospective Retrospective Retrospective Retrospective Prospective Retrospective
153 139 342 176 223 101 200 567 603 103 142 254 174 143 151 217 199 2029 148 1043 544 128
0/100 NR 0/100 100/0 100/0 50/50 100/0 9/91 0/100 100/0 83/17 25/75 0/100 50/50 100/0 100/0 52/48 0/100 100/0 5/95 16/84 46/54
NR
1996-1999 1990-1997 1996-1998 1985-2001 2002-2003 1992-2002 1999-2009 1996-2008 2002-2007 2001-2008 2005-2007 1998-2006 2006-2009 1990-2008 2004-2007 2001-2009 2010-NR 1992-2011 2004-2010 2001-2010 2011 2001-2011
4 years 8 years 3 years 16 years 2 years 11 years 11 years 13 years 5 years 8 years 3 years 9 years 4 years 19 years 4 years 9 years NR
High High Low High High High Low Low Low High Low Low High Low High Low High High Low Low High High
NR
16 months 23 months NR
8 months NR NR
19 months 26 months NR
36 months 9 months 21 months NR NR NR NR
24 months 72 months NR NR
20 years 7 years 10 years 1 year 11 years






































































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