Page 98 - Characterization of genetic neurodevelopmental disorders at adult age, with a focus on 22q11.2 deletion syndrome - Emma Boersma
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Chapter 2
sTable 4. Quality assessment of observational cohort and cross-sectional studies
First author
Year of publication
Journal
Clear research question
Clear subject population
At least 50% participation rate
Subjects recruited from the same
population.
Prespecified in/ exclusion criteria
Sample size justification, power
description, variance/effect
estimate
Exposure(s) of interest measured
prior to the outcome(s) being
measured
Boot 2018 Neurology + + na + na na
Butcher 2013 JAMA Neurol + + + + + na
Clot 2009 Brain + + cd + na na
Fasano 2014 Neurology + cd cd + na na
Fitzgerald 1990 Movement disord + + + + na na
Gitiaux 2008 Movement disord + + cd + na na
Hayflick 2013 Brain + + na + na na
Kara 2016 Brain + + cd + na na
Lai 1989 Arch neurol + + + + na na
Martikainen 2016 JAMA neurol + + + + na na
Nishioka 2015 Neurobiol Aging + + na + na na
Olgiati 2016 Ann neurol + + cd + na na
Utari 2010 J neurodevelop
disord
+ + cd + na na
Vieregge 1991 J neurol neurosur
ps
+ + cd cd na na
Abbreviations: yes (+) / no (-) / cannot determine (cd) /not applicable (na) / not reported (nr).
G=Good, F=Fair.
tools.
Source assessment form: https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-
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