Page 141 - Demo

Hearing loss and otolaryngological conditions1394peak occurring at a negative middle ear pressure (type C), 3 (12.5%) had abnormally high admittance with normal tympanometric pressure (type Ad), 2 (8.3%) had abnormally low admittance with no discernable peak (type B), and 1 (4.2%) had abnormally low admittance with normal tympanometric pressure (type As).Otolaryngological conditions and treatmentsThe majority of the study sample had history of one or more otolaryngological conditions (Table 3). Chronic/recurrent otitis media was reported most often (n=34, 56.7%), followed by hearing loss (n=19, 31.7%), globus pharyngeus (n=11, 18.3%), balance problems (n=10, 16.7%), swallowing difficulties (n=6, 10.0), obstructive sleep apnea (OSA, n=5, 8.3%), and nasal regurgitation (n=5, 8.3%). Table 3. Lifetime history of otolaryngological conditions and treatments in 60 adults with 22q11.2 deletion syndromeConditions Number % 95% CIChronic/recurrent otitis mediaHearing lossGlobus pharyngeusBalance problemsSwallowing difficultiesObstructive sleep apneaNasal regurgitation3419111065556.731.718.316.710.08.38.344.1 – 69.219.9 – 43.48.5 – 28.17.2 – 26.12.4 – 17.61.3 – 15.31.3 – 15.3Treatments Number % 95% CISpeech-language therapy a Speech Feeding/swallowing Indication not specifiedENT-surgery Ear tube placement Pharyngoplasty Tonsillectomy Tympanoplasty/myringoplasty Palatoplasty Adenotomy Nose/septum surgery Ear reconstruction surgery Laryngeal web resection Tracheotomy and vocal cord surgery MastoidectomyHearing aid Bilateral Unilateral4740774323 17997622111 54178.366.711.711.771.738.328.315.015.011.710.03.33.31.71.71.78.36.71.767.9 – 88.854.7 – 78.63.5 – 19.8 3.5 – 19.860.3 – 83.126.0 – 50.616.9 – 39.76.0 – 24.06.0 – 24.0 3.5 – 19.82.4 – 17.60.0 – 7.90.0 – 7.90.0 – 4.90.0 – 4.90.0 – 4.9 1.3 – 15.30.3 – 13.00.0 – 4.9a Seven adults with 22q11.2DS received speech-language therapy for both speech and feeding/swallowing issues. ENT=ear-nose-throat, CI=confidence interval.