Page 141 - Coronary hemodynamics in acute myocardial infarction - Matthijs Bax

Elevated glucose levels impact microvascular function in STEMI
with CFVRreference. After adjustment for these variables, admission glucose level remained independently associated with CFVRreference (std beta=−0.313; p = 0.002), bAPVreference (std beta = 0.216; p = 0.033), BMRreference (std beta = −0.225; p = 0.038) and dMRreference (std beta = −0.274; p = 0.008) (Tab. 3).
Table 3. Association between reference CFVR and glucose by univariate and multi-variate analysis at admission, 1 week and 6 months follow-up
At 1-week follow-up (n=61)
Multivariable Analysis
Std P Beta value
-0.381 < 0.001 -0.2540.015------
At admission (n=92)
At 6-months follow-up (n=61)
Multivariable Analysis
Std Beta P value
Univariable Analysis
Std Beta P value
CFVR in reference vessel
Multivariable Analysis
Std Beta P value
Glucose
Age
Heart rate
Peak troponin T (after 24h) WMSI
Calcium
antagonist
Baseline APV in reference vessel
Glucose 0.244 0.02 0.216 0.033 - - - - Age --------
Heart rate
Peak troponin T
(after 24h) WMSI
Calcium antagonist
-0.318 0.004 -0.244 -0.376 < 0.001 -
-0.357 0.001 -0.223 -0.299 0.005 -0.247
0.023 -
0.041 0.016
-0.225 -0.469
0.034 < 0.001
- - -0.355 0.002
-0.413 0.002 - -
- - - -
0.241 0.026 0.349 0.001
--
0.266 0.385
0.014
- -
- -
-0.278 0.042
-0.313 0.002
- -
- -
-0.265
-0.381 < 0.001 - - - - - -
Heart rate
Peak troponin T
(after 24h)
WMSI 0.316 0.003
Calcium
antagonist
Baseline MR in reference vessel
Glucose -0.257 0.015
Age --------
- - - -
- - - -
- - - -
- -
- - - -
-0.326 0.003 -0.295 0.006
-0.246 0.035 -0.292 0.008
-- --
- - - -
-0.225 0.038
- -
Heart rate
Peak troponin T
(after 24h)
WMSI
Calcium
antagonist
Delta MR in reference vessel
Glucose -0.325 0.002
Age --------
-0.262 0.02 -0.228 0.038
-0.229 0.045 - -
-0.269 0.044 -0.346 0.022
- - - -
-0.274 0.008
--
-0.320 0.015 -0.336 0.022
-- --
- -
- - - -
- - - -
0.014 < 0.001
- - 8 - -
Std beta: standardized beta coefficient; CFVR: coronary flow velocity reserve; APV: average peak velocity: MR microvascular resistance; WMSI: Wall Motion Score Index.
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