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TB prevalence in LA was lower in men than in women (2.8 vs. 4.2% respectively); in contrast to the global study in which the prevalence was higher in men (3.0 vs. 1.6% respectively). Cases of TB in LA were observed after the age of 35 and homogeneously distributed among all age groups regardless of gender (in total: 7 cases of TB in males and 6 cases in females). Seven of these cases were reported in Argentina and six in Colombia. In contrast in the ASAS-COMOSPA-study, TB cases were reported as early as at an age of 25 years and were more frequent in men (78 male and 23 female cases). The average risk of TB was 10.3 times higher in SpA patients than in the general- population. The risk was more increased in women than in men (18.2 vs. 6.8 respectively) and was found in all age categories except in patients ≥65 years in whom the risk declined in both genders.
Table 3. Observed prevalence of TB in the ASAS-COMOSPA study (Latin America*) compared with the expected prevalence in general population and prevalence of Global ASAS-COMOSPA for reference.
Gender
Men
Women
Age groups 20-24 25-34 35-44 45-54 55-64
≥65
Total men
20-24 25-34 35-44 45-54 55-64 ≥65 Total women
Observed
LA ASAS-COMOSPA
n (%)
00
0 0
2 3.3 2 4.3 2 7.4 1 4.0 7 2.8
00
0 0
2 5.6 1 2.8 2 7.4 1 7.1
6 4.2 13 3.3
Expected General population
Prevalence (%) 0.29
0.21
0.23
0.40
0.73
1.14
0.41
0.22 0.13 0.15 0.19 0.37 0.41
0.23 0.32
SRR (CI 95%)
-
- 14.3 10.7 10.1 3.5
6.8 (3.2-13.9)
-
- 37.3 14.7 20.0 17.3
18.2 (8.5-40.6) 10.3 (6.1-17.8)
Global ASAS- COMOSPA
n (%)
00 16 2.7 15 2.4 18 3.1 12 3.1 17 7.1 78 3.0
00
1 0.4 4 1.1 6 1.7
11 4.8 1 0.7
23 1.6 101 2.5
Total men/women
n= number with a history or current active TB
Prevalence (%); SRR, standardized risk ratio; LA*, Latin America
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