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Figure 2b Dot-plot illustrating the number of ASAS core-set instruments per trial according to the date of publication and type of intervention. Miscellaneous interventions in this context, include physical therapy and other kind of treatments. Glucocorticoids are included in DMARDs interventions. All studies (n=99).
ASAS-endorsed response criteria and other outcomes
Since the ASAS response criteria and partial remission criteria were published in 2001 (ASAS 20 and ASAS partial remission criteria) and in 2004 (ASAS 40 and ASAS 5/6), only studies published two years after those dates (n=45 and n=33 respectively) were included in the analyses (in this context only trials from the ‘implementation group’ were investigated). ASAS 20 response criteria were reported in 40% of the trials (18 out of 45 trials), ASAS 40 in 45% (15 out of 33) of the trials, ASAS 5/6 in 30% (10 out of 33) and ASAS partial remission in 22% (10 out of 45). The reported percentages for each response criteria are different mainly due to the publication date and the implementation time. The number of trials reporting the response criteria are not the same -e.g. ASAS 20 (45 trials) and ASAS 40 (30 trials).
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