Page 118 - Helicobacter pylori and Gastric Cancer: From Tumor microenvironment to Immunotherapy

Chapter 5
Chapter 5
Cancer risk-oriented atrophy grading
When classified according to cancer risk-oriented atrophy grading defined above, 110 (88.1%) of the 248 patients were concordant (Tables 5 and 6). The strength of agreement between endoscopic and histological assessment by cancer risk-oriented grading showed good reproducibility, with a weighted kappa value of 0.79 (95%CI: 0.60–0.97). No marked differences between the two geographical locations involved appeared. Thus with respect to assessing cancer risk endoscopic evaluation performs well irrespective from the geographical context.
Table 5. Endoscopic and histological atrophy cross tabulation according to populations with H pylori associated gastric atrophy
Histological atrophy
Total
Weighted κ value
Nigeria
None
Antrum
Angulus
Middle body LC
Middle body GC
Endoscopic atrophy
No atrophy
40
4
4
2
0
56
0.79
Antrum
8
30
5
0
0
40
Antrum predominant
0
2
3
0
0
24
Corpus predominant
4
0
10
12
0
6
Total
52
36
22
14
0
124
Iran
Endoscopic atrophy
No atrophy
31
17
10
09
0
67
0.96
Antrum
10
12
4
10
0
36
Antrum predominant
0
0
0
0
0
0
Corpus predominant
8
3
0
10
0
21
Total
49
32
14
29
0
124
112
116