Page 130 - Physiological based CPAP for preterm infants at birth Tessa Martherus

Chapter 5
Mean airway pressure and mask leak (Figure 5)
Comparing the modes of respiratory support, mean airway pressures (MAP) were significantly higher during iPPV (16.2 (15.4-17.8) cmH2O) than during 5-8 cmH2O CPAP (7.8 (7.3-8.4) cmH2O) but did not differ with 15 cmH2O CPAP (13.8 (13.7-14.6) cmH2O, p=0.006). During iPPV, there was significantly more mask leak than when 5-8 cmH2O CPAP was given with the difference being 10 (2-20)% (p=0.010). There was no significant difference in the amount of leak created during 15 cmH2O and 5-8 cmH2O CPAP (leak difference, 4 (-1-17) %, p=0.345).
Figure 4. Outcomes of respiratory effort. Outcomes of a) respiratory effort breathing rate, b) inspiratory tidal volume (Vti) and c) minute volume (MV) of infants receiving PB-CPAP and 5-8 cmH2O CPAP following the per-protocol analysis.
Figure 5. Mean airway pressure and leak. a) Mean airway pressure and b) per respiratory support mode. Leak per respiratory support mode is calculated as difference in leak compared to 5-8 cmH2O CPAP as it is calculated within infants.
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