Page 80 - Quantitative Imaging of Small Tumours with Positron Emission Tomography
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                                Supplemental files PVC in dynamic PET-CT  3   Supplemental Figure 3.1: Time-activity curves of intralesional image noise (COV%) without and with PVC using several HYPR settings. Frames of 0-4 minutes (A) and 4-60 minutes (B) post-injection. Results of a typical mediastinal lymph node metastasis are shown. Supplemental Table 3.1: Spearman correlations between IDIF AUCs of PVC-images and uncorrected images. All correlations were significant with p<0.001.  Entire curve Peak only (2.5 min)   LR LR+HYPR (-/+ 3 frames) LR+HYPR (single composite) Image-derived 0.994 0.994 0.994 Calibrated 0.991 0.990 0.992 Image-derived 0.993 0.992 0.997 Calibrated 0.988 0.987 0.996  Supplemental Table 3.2: Median relative differences (% with IQR) in K1, Vt, and k3/k4 of uncorrected images using uncorrected versus corrected IDIFs (PVC without and with HYPR denoising). *p<0.05 Wilcoxon-signed-rank test.  IDIF: LR LR+HYPR (-/+ 3 frames) LR+HYPR (single composite) K1 2.9 (0.2 to 7.4)* 3.1 (0.9 to 5.5)* 0.0 (-0.2 to 0.1) Vt 0.9 (-1.1 to 2.6)* 1.1 (-0.4 to 4.5)* 0.0 (0.0 to 0.1) k3/k4 -0.2 (-3.7 to 2.4) -0.8 (-3.2 to 1.6) 0.1 (-0.1 to 0.1)   79     


































































































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