Page 104 - Coronary hemodynamics in acute myocardial infarction - Matthijs Bax

Chapter 6
Table 1. continued
Baseline APV target vessel, cm/s Hyperemic APV target vessel, cm/s
FFR
CFVR reference vessel
Baseline APV reference vessel, cm/s
Hyperemic APV reference vessel, cm/s HSR, mmHg/cm per second
Reference vessel diameter, mm
Microvascular resistance
Target vessel
Baseline MR, mmHg/cm per second Hyperemic MR, mmHg/cm per second
Reference vessel
Baseline MR, mmHg/cm per second Hyperemic MR, mmHg/cm per second
PCI of target lesion
Reference CFVR
All
17±8 36±17
0.73±0.17 2.9±0.7 18±7 50±17 1.33±2.28 2.9±0.6
6.01±3.04 2.29±1.21
6.16±2.30 2.14±1.02 64 (36)
Normal
>2.7
15±6 35±16
0.73±0.17 3.4±0.4 16±5 52±18 1.16±1.66 2.9±0.6
6.49±2.61 2.18±0.78
6.92±2.42 2.07±1.19 35 (35)
Abnormal
≤ 2.7
20±10 38±19
P value*
<0.001 0.41
0.73±0.18 0.98 2.3±0.3
21±7
48±16 0.23
1.54±2.88 0.30 2.9±0.7 0.72
5.40±3.44 0.02 2.42±1.60 0.22
5.21±1.73 <0.001 2.22±0.76 0.35 29 (38) 0.75
<0.001
Values presented as n (%) or mean±SD. ACE indicates angiotensin-converting enzyme; APV, average peak flow velocity; CAD, coronary artery disease; CFVR, coronary flow velocity reserve; EF, ejection fraction; FFR, fractional flow reserve; HSR, hyperemic stenosis resistance index; MPS, myocardial perfusion scintigraphy; MR, microvascular resistance; and PCI, percutaneous coronary intervention.
*P value for comparison between normal and abnormal reference vessel CFVR groups.
Table 2. Reference Vessel Location Relative to the Target Vessel.
Target vessel
LAD LCX RCA
LAD
... 25 (14) 22 (12)
Reference vessel
LCX
79 (44) ... 28 (16)
RCA
13 (7) 11 (6) ...
Data presented as n (%). LAD indicates left anterior descending coronary artery; LCX, left circumflex coronary artery; RCA, right coronary artery.
Coronary Flow Velocity Parameters
Reference vessel APV under baseline conditions was significantly higher, and microvascular resistance under baseline conditions was significantly lower among patients with an abnormal reference vessel CFVR (Table 1). Contrariwise, reference vessel hyperemic flow velocity and reference vessel hyperemic microvascular resistance were similar between both groups (Table 1).
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