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Subcortical-PFC resting state connectivity
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showed moderate influences of genetics (A=23%, C=0%, E=77%), and AMY-OFC connectivity showed high heritability (A=54%, E=46%), see Table 5.
Figure 3. Subcortical-cortical and subcortical-subcortical brain connectivity. A) Connectivity between subcortical seeds (ventral striatum (VS) and amygdala (AMY)) and prefrontal cortical regions ventral medial prefrontal cortex (vmPFC), ventral anterior cingulate cortex (vACC), orbitofrontal cortex (OFC), dorsal medial PFC (dmPFC), dorsal ACC (dACC) and dorsal lateral PFC (dlPFC). B) Connectivity between VS, AMY, hippocampus and thalamus. Error bars represent standard error of mean. Asterisks indicate significant differences between samples.
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