Page 237 - Prevention and Treatment of Incisional Hernia- New Techniques and Materials

Table 1. Postoperative mortality and number of animals analysed at 28 and 90 days after surgery
Meshes in a contaminated environment
No. analysed
Group
Control
Strattice
Parietene
Parietene composite
Sepramesh C-Qur
Dualmesh Omyramesh Total
Mesh material
-
Non-crosslinked collagen
Polypropylene
Collagen–polyethyleneglycol– glycerol-coated polypropylene
Carboxymethylcellulose–sodium hyaluronate-coated polypropylene
Omega-3-fatty acid-coated polypropylene
Expanded polytetra uoroethylene Condensed polytetra uoroethylene
# Postoperative death
28 days
8 7 8 7
8
8*
7
7 60
90 days
8 7 8 7
8 8
8
8 62
*One rat in the C-Qur® group died after 13 days. The results for this rat were for rats killed after 28 days in the C-Qur® group.
Mesh infection
analysed together with those
At the time of death macroscopic infection of the mesh was present in 24 (22.6%) of 106 animals. The infection rate among C-Qur® meshes was high (15 of 16 rats) compared with all other meshes (P ≤ 0.006) (Figure 1). Dualmesh® also showed a high infection rate (7 of 15 rats), signi cantly higher than all other groups apart from C-Qur® (P ≤ 0.035). All infected meshes became large brotic pseudotumours. No additional mesh infection was discovered by microbiological culture of the meshes.
Abscesses
Intra-abdominal abscesses were found in 37 rats (62%) after 28 days and 27 (44%) after 90 days (P = 0.049).The majority of abscesses were located at the caecum or abdominal wall. There was no signi cant di erence between groups in intra-abdominal abscesses (P = 0.482).
11
18 2
18 4
18 2
18 4
18 2 18 2
18 3
18 3 144 22
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