Page 223 - Prevention and Treatment of Incisional Hernia- New Techniques and Materials

Figure 6. Histologic samples after picrosirius red staining at 90 days. The collagen layer between mesh and abdominal wall is indicated by c. Collagen surrounding Surgisis mesh is shown by asterisk.
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Biological mesh in hernia repair
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Adhesions are formed during the in ammatory phase in the rst 7 days after surgery(24). This period is followed by the proliferation phase until about day 30, when some regression is observed, whereas the remaining adhesions become more organized to brous and vascularized tissue. In general, previous opinion maintained that this succeeding phase of remodeling was temporary and that inert scar tissue was nally formed. However, ndings recently have shown that even after months to years, macrophages, broblasts, mononuclear cells, and neovascularization can be identi ed in abdominal adhesion tissue, suggesting a dynamic and ongoing process of remodeling(25-27). This is
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