Page 217 - Prevention and Treatment of Incisional Hernia- New Techniques and Materials

coe cient. All reported p values are two-sided and considered signi cant if lower than 0.05. Statistical analysis was performed using the PSAW 17 statistical software package (IBM SPSS statistics, Amsterdam, The Netherlands).
Results
During this study involving 85 animals, no animals died prematurely.
Adhesions
At 30 days, Parietex composite showed a signi cantly smaller percentage of mesh surface covered with adhesions (9 %; IQR, 3.0–12.8 %) than any of the other meshes. Permacol resulted in signi cantly more adhesions than any of the other meshes (87.5 %; IQR, 81–100 %), and adhesion coverage with the Prolene mesh was signi cantly higher than with Strattice (40 %; IQR, 24.1–61.5 %) or Parietex composite meshes. Surgisis mesh showed 45 % coverage (IQR, 7.4–77.5 %) of the mesh surface.
At 90 days, the smallest amount of adhesions was seen with Parietex composite (5 %; IQR, 2–5 %) and Strattice (5 %; IQR, 4–10 %), signi cantly less with either Prolene (42 %; IQR, 36.8–53.6 %) or Permacol (74.8 %; IQR, 37.9–82.7 %) (Figure 1). Five Surgisis meshes showed 100 % adhesion coverage, whereas two meshes were completely adhesion free. Compared with the results at 30 days, Prolene, Strattice, and Permacol showed a signi cant reduction in the amount of adhesions at 90 days (Figure 1). Figure 2 shows representative views of all the meshes at the long-term follow-up evaluation.
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Biological mesh in hernia repair
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