Page 168 - Pro-active Management of Women’s Health after Cardiometabolic Complicated Pregnancies

166 | Part 3 Lifestyle intervention
Table 3.5.2. Effect of lifestyle intervention program
Parameter
Weight
BMI
Waist-to-hip ratio
Systolic blood pressure Diastolic blood pressure Blood pressure medication Heart rate
Total cholesterol LDL-cholesterol HDL-cholesterol
HDL/total cholesterol ratio Triglycerides
Fasting glucose
75 gr-OGTT 2-hour value Abnormal glucose (DM-2) HOMA2-score
CRP
Urinary protein/creatinine ratio Total protein in 24-hour urine
Smoking Physical activity Physical activity Fat intake total Fat intake snacks
Unit
kg kg/m2 cm/cm mm Hg mm Hg %
bpm
mmol/L mmol/L mmol/L mol/mol mmol/L mmol/L mmol/L %
%S mmol/L g/mol g/24h
%
MET steps/day g/day g/day
Intervention group (n=144)
6 months
81±20 28±7 0.83±0.06 120±12 77±10 9% 75±11
5.0±0.9 3.1±0.8 1.4±0.3 3.9±1.2 1.3±0.9 4.9±0.6 5.2±1.2 14% 130±106 5.7±9.4 12±23 113±207
15% 3672±6554 8290±2508 17.0±5.1 6.2±3.0
13 months
77±19 27±6 0.81±0.07
p-value
<0.001 <0.001 <0.001
117±12 0.09 75±8 0.10 16% 0.02
71±8 <0.01
4.6±0.8
2.9±0.7
1.3±0.4 0.50 3.7±1.2 0.08 1.2±1.0 0.07 4.9±0.9 0.31 5.0±1.7 0.54
12% 0.45 144±111 0.57 5.7±8.1 0.76 12±23 0.40 116±159 0.58
14% 0.74 3830±4240 0.07 8658±2099 0.47
15.1±5.1
5.5±3.0 <0.01
<0.001 <0.001
<0.001
group. After adjustment for the change in controls, baseline weight, duration of breastfeeding, preeclampsia and severity of preeclampsia and gestational age at delivery, a significant decrease of 1.9 kg (0.3 to 3.4) could still be attributed to the lifestyle intervention. BMI and waist-to-hip ratio also significantly decreased, which remained after adjustment. Total and LDL-cholesterol changed significantly in the intervention group. However, after adjustment for the mentioned confounders this change was no longer significant. The change in HOMA2-score in the intervention group became significant after adjustment for the mentioned confounders. Lifestyle habits all showed favourable trends in the