Page 164 - Pro-active Management of Women’s Health after Cardiometabolic Complicated Pregnancies

162 | Part 3 Lifestyle intervention
different demographic variables between the case and control group (model 2). This analysis was repeated for all secondary outcome measures, where the baseline weight measure was replaced by the baseline measure of the dependent variable. Results are presented as mean change and 95% confidence interval.
During the study we experienced lower adherence in the control group than expected. To compensate, we multiple imputed the 13-month measures for participants who had attended the visits at 6 and 10 months postpartum. The imputation model was based on the mean and standard deviation of participants who attended all visits, with a random generated z-score. Sensitivity analysis was performed by comparing the findings with the analysis without imputation. Three random iterations of imputation were done. Significant findings were only reported, if all 3 iterations showed significant results.
The study was funded by a research grant of ZonMw (61200024). Ethical approval was granted by the institutional review board of the Erasmus University Medical Centre (2006-164) and the participating secondary care hospitals.
RESULTS
Table 3.5.1 summarizes the demographics and baseline measures at enrolment. Significant differences between the intervention and control group were observed for ethnicity, marital status, birth weight, frequency of preeclampsia and severe preeclampsia and gestational age at delivery. Furthermore, the groups significantly differed in weight, systolic blood pressure and diastolic blood pressure at baseline measurement.