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3.2 Effect of Lifestyle Interventions after Preeclampsia| 99
Figure 3.2.1. Steps in estimating the contribution of cardiovascular risk factors, additive cardiovascular risk of preeclampsia and the effect of lifestyle interventions on future cardiovascular disease (numbers correspond with numbered steps in text).
2010 were included, and Non-English and non-human studies were excluded.
In step 1b we calculated the difference in cardiovascular risk factors between women with a history of preeclampsia and women with a history of a healthy pregnancy by subtraction. For each cardiovascular risk factor, the median value and interquartile range of the reported differences was calculated. This resulted in a collection of median differences of the cardiovascular risk
factors as shown in the first column of table 3.2.1.
In step 1c we searched for cardiovascular risk prediction models. A recent
review by Cui et al203 was used to identify validated cardiovascular risk prediction models. An additional hand search provided the Framingham 30-years prediction model39. We used the original articles that reported on the