Page 121 - Recognizing axial spondyloarthritis - Janneke de Winter

Fulfilling the ASAS axSpA and/or ESSG criteria
Fulfilling vs not fulfilling the ASAS axSpA and/or ESSG criteria
0.704
0.361 0.874 0.695 0.169
-
0.014 - 0.473 0.007 -
THE PRE-SPA COHORT
Study population
2.37 (3.45)
6 (12) 6.72 (7.16) 4 (8) 345.44 (129.85)
0 (0)
3 (6)
0 (0)
1 (2) 10 (20) 0 (0)
ASAS, Assessment of
Spondylitis Disease Activity Score; AxSpA, axial spondyloarthritis; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; BMI, body mass index; cm, centimeter; CRP, c-reactive protein; DMARD, disease modifying antirheumatic drugs; ESR, erythrocyte sedimentation rate; ESSG, European Spondyloarthropathy Study Group; IBD, inflammatory bowel disease; HLA-B27, human leukocyte antigen-B27; kg, kilogram; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; m, meter; mm, millimeter; MRI, magnetic resonance imaging; NSAIDs, non-steroidal anti-inflammatory drugs; PGA patient global assessment of disease activity; PhGA, physician global assessment of disease activity; SD, standard deviation; SIJ, sacroiliac joints; SJC, swollen joint count; SpA, spondyloarthritis; TJC, tender joint count; TNF, tumor necrosis factor; VAS, visual analogue score. Data presented as n (%) unless otherwise specified.
Table 2. Clinical characteristics, laboratory and imaging results of the FDRs with and without imaging abnormalities on X-ray and/or MRI of the SIJ and spine
Laboratory
CRP, mg/L, mean (SD)
CRP above 5 mg/L ESR, mm/h, mean (SD) ESR above 20 mm/h Calprotectin, ng/mL, mean (SD) Calprotectin above 715 ng/ml
Imaging
Low grade sacroiliitis on X-ray Syndesmophytes of the lumbar spine on X-ray Syndesmophytes of the cervical spine on X-ray Inflammatory lesions of the SIJ on MRI Inflammatory lesions of the spine on MRI
1.94 (2.71)
1 (6)
6.41 (6.16) 1 (6) 310.03 (136.07)
0 (0)
3 (17.6) 0 (0)
0 (0)
7 (41) 0 (0)
2.58 (3.79)
5 (15) 6.88 (7.71) 3 (9)
364 (125)
0 (0)
0 (0) 0 (0) 1 (3) 3 (9) 0 (0)
SpondyloArthritis international
Society; ASDAS, Ankylosing
Demographics
Male gender
Imaging abnormalities
Yes (n= 12) No (n= 38) p-value
6 (50) 19 (50) -
Table 2 continues
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