Page 152 - ADULT-ONSET ASTHMA PREDICTORS OF CLINICAL COURSE AND SEVERITY

ADULT-ONSET ASTHMA – PREDICTORS OF CLINICAL COURSE AND SEVERITY
Table 4. Univariate and multivariate logistic regression analysis of potentially associated factors. Table 4. Univariate and multivariate logistic regression analysis of potentially associated factors.
(Ex)smokers (Ex)smokers
Univariate analysis CUhnroivnairciaOtCeSaunsaely, syiess
BChlorodninceOuCtrSoupsheil,syes IBClSooddosneu(pterorp1h0i0lsμg) IACsSthdmosaed(upreart1io0n0, μyega) rs APbstFhEmVa1 d%urparteiodnic,tyeedars PAbtoFpEyV,1ye%s predicted Atopy, yes
Multivariate analysis BMlouoldtivnaeruiatrtoepahnilaslysis
IBCloSoddosneu(pterorp1h0i0lsμg)
ICS dose (per 100 μg) Multivariate odds ratios
are analysed in absolute Multivariate odds ratios
are analysed in absolute
Never smokers Never smokers
Univariate analysis
BUlonoivdaerioastienoanphalilyssis BChlorodniecoOsiCnSoupsheil,syes AChCrQo-n6icscOoCreS use, yes IACCSQd-o6ssec(oprer 100 μg) PICbSFdEoVs1e %(pepre1d0i0ctμegd)
MPbeFthEVach%olipnrePdCic2te0d 1
Methacholine PC20
Multivariate analysis
BMlouoldtiveaorsiiantoepahnilaslysis Blood eosinophils
OR
5O.2R6 1.80
51.2560 1.8102 1.1560 1.0152 1.0146 1.050 01.9084 10.0906 0.9484 0.916 0.44 0.16
95% C.I. p-value
95% C.I.15.36
125..0326 12.2092 1.2098 1.080 1.0108 1.18
p0-v.0a0lu2e 0.0026 0.0056 0.00459 0.04792 0.01702 0.102
p-value p0-v.0a1lu0e
OR 95% C.I. 1O.5R1 1.1905% C.I. 2.08
1.5118 1.1005 21.0382 0.01005 1.18 1.05 1.32 0.005
are adjusted for OCS use and asthma duration. Blood neutrophils
numbers.
are adjusted for OCS
numbers.
use and asthma duration. Blood neutrophils
OR
1O8R.9 21.83.79 12.7317 1.171 10.1918 0.9882
0.82
95% C.I
95% C.I 202.1 260.823.1 36.1873
13.2137 1.2030 1.007
1.07 95% C.I.
p-value p0-v.0a1lu5e 0.011059 0.019019 0.04931 0.04935 0.019459 0.149
p-value
p0-v.0a1lu5e 1.8 202.1 0.015
1.77 01.8727 0.982 10.0902 10.0905 0.9653
0.63
OR
1O8R.9
1.8 95%2C0.2I..1
18.9
Multivariate odds ratio is adjusted for ICS dose. Blood eosinophils are analysed in absolute
numbers.
Multivariate odds ratio is adjusted for ICS dose. Blood eosinophils are analysed in absolute
numbers.
4 4
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