Page 136 - ADULT-ONSET ASTHMA PREDICTORS OF CLINICAL COURSE AND SEVERITY
P. 136
ADULT-ONSET ASTHMA – PREDICTORS OF CLINICAL COURSE AND SEVERITY
SUPPLEMENTARY MATERIAL
METHODS
ASTHMA SEVERITY SCORE
Assessment of asthma severity was based on the GINA 2002 guidelines.(E1) Classi ca on takes three steps: the rst step is to determine each pa ent’s treatment category, based on the daily dose of inhaled cor costeroids (low, medium or high).(E2) Secondly, symptom score and FEV are
1 assessed: 1) intermi ent symptoms or FEV1 >80% predicted, 2) mild persistent symptoms or
FEV1 >80%, 3) moderate persistent symptoms or FEV1 60-80%, 4) severe persistent symptoms
or FEV1 <60%. The nal step is to combine clinical severity of step 2 with medica on dose of
step 1 into an overall category (Figure E1).(E1)
Repository E Figure No.
Fig E1. Asthma severity score according to the GINA guidelines (2002)(E1).
Categorization is based on a composite score of treatment with symptoms and lung function. The presence of one feature of severity is sufficient to place a patient in that category.
134
