Page 215 - Clinical relevance of current materials for cranial implants

Flexural strength, flexural modulus and impact strength were measured. The flexural strength of all materials studied was significantly increased by gamma-irradiation as compared to the non-sterilized specimens. NextDent C&B MFH had the highest flexural and impact strength. Palacos R + G demonstrated the highest maximum stress intensity and total fracture work. It was concluded that autoclave sterilization should not be used because of the deformation of the material due to the high temperature and pressurized steam. Ethylene oxide, hydrogen peroxide plasma gas and gamma- irradiation, are preferable methods for sterilization of PMMA-based medical implants.
Part V: General discussion
This thesis ends with chapter 10, in which the research findings are discussed and future perspectives on these topics are delineated. The need for clear definitions, protocols and guidelines is argued, current used different materials are criticized and characteristics of the ideal material for cranioplasties is highlighted. Possible technological innovations are presented. In the future perspectives a proposal for a Delphi Study, RCT and new in vitro study is described. Followed by possibilities of bioprinting for cranioplasties. A case in which manufacturing the cranioplasty of the future is presented at the end of the future perspectives.
This chapter ends with the conclusion of this thesis: an ideal and safe cranioplasty material needs to be developed for the long-term protection of the brain.
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Summary & Nederlandse samenvatting
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