Page 38 - Sentinel lymph node biopsy in oral cavity cancer - Inne J. den Toom

Chapter 2 contained macrometastasis (Table 2). One patient with a lateralized T1 tumour of the tongue demonstrated ITC in a SLNB in the contralateral neck. Table 2. Additional metastases in neck dissection specimen related to metastasis type in SLNB Metastasis in SLNB Isolated tumour cells Micrometastasis Macrometastasis Total Neck dissection Selective Selective Modified I-III I-IV Radical 2 2 00 4 4 04 0 3 06 6 9 10 Total, n (%) 04 (15%) 12 (46%) 09 (36%) 25 Metastases in ND specimen 0 0 5 (56%) 5 (20%) SLNB, sentinel lymph node biopsy; ND, neck dissection Table 3. Data of patients with regional recurrence during follow-up SLNB Recurrence time (months) Positive 06.8 Positive 04.7 Positive 02.2 Negative 51.3 Negative 03.1 Management Treated with salvage neck dissection and CRT. Alive and disease free. Treated with CRT. Deceased by distant metastasis. During PORT, contralateral metastasis were found. Treated with salvage neck dissection and PORT. Deceased by distant metastasis. Patient withdrew from follow-up for 4 years. Salvage neck dissection for N3 neck disease. Patient refused PORT. He is still alive. Treated with salvage neck dissection and PORT. Alive and disease free. SLNB, sentinel lymph node biopsy; CRT, chemoradiotherapy; NED, no evidence of disease; PORT, postoperative radiotherapy 36