Page 46 - Timeliness of Infectious Disease Notification & Response Systems - Corien Swaan

44 Chapter 2
Comparing the timeliness of a total of 1533 HBV infection reports to MHS in 2008, with respect to the presence or absence of physician laboratory agreements, MHS with agreements showed a significant reduction in notification time by 5.3 days (p< 0.01; 95% CI 1.7-8.9 days), compared to MHS without agreements.
Table 2. Percentage of notifications within one or two intervals corrected for the period of infectiousness before disease onset (Ic) for measles and hepatitis A virus infections, with the percentage assuming zero delay in laboratory reporting (underlined percent- ages in italics).
Measles (Ic 7 days)
HAV infection (Ic 14 days)
n=134
n=1518
percentage notifications
≤ 1 Ic (%)
48.5
71.4
60.4 78.7
percentage m notifications
≤ 2 Ic (%)
71.6 73.9 0 90.3 93.1 65
Ic (I-corrected)= LP (latent period)-x (period of infectiousness in index patient preced- ing symptom onset)
n = total number of notifications
m = number of missing i.e. excluded notifications
Table 3 . Mean reporting time intervals from symptom onset and from diagnosis until notification (Po and Pd) for infectious disease notifications per year for shigellosis and hepatitis A virus infection.
2003 21.2
2004 21.7
2005 20.0
2006 22.2
2007 19.9
2008 21.3
18.2-24.1 18.9-24.6 17.9-22.1 19.0-25.4 18.1-21.6 18.3-24.3
189 4.4 3.6-5.2 336 4.5 3.8-5.1 388 4.0 3.4-4.7 238 3.8 3.1-4.5 382 4.1 3.4-4.8 372 2.9 2.5-3.2
189 12.5 11.1-13.8 339 14.5 12.3-16.6 388 15.2 12.2-18.2 239 15.1 13.2-16.9 383 13.2 11.1-15.3 372* 14.1 11.3-16.9
Shigellosis
Po 95% CI (days)
Hepatitis A virus infection
n Pd 95% CI
(days) (days)
n Po 95% CI
nPd 95% CI n (days)
2492.7 2.1-3.3 258 4203.8 2.4-5.1 439 2023.0 1.5-4.6 212 2612.4 1.5-3.3 277 1531.7 1.0-2.4 157 1681.7 1.3-2.2 174
Po=period from symptom onset until notification Pd=period from laboratory diagnosis until notification
* p<0.05 for 2008 versus 2003 and 2004 n= number of notifications