Page 85 - Assessing right ventricular function and the pulmonary circulation in pulmonary hypertension Onno Anthonius Spruijt

Characteristics of the 38 patients with a second set of a CMRI and echo are summarized in the online supplement (table A). The median (IQR) time between the first measurements and the second measurements was 192 (129-570) days. The time between the second CMRI and second echo was 2±6 days. The change in CMRI-derived-RVEF was significantly related to the change in all four echo parameters (figure 4), with the strongest relation found between the change in CMRI-derived-RVEF and the change in RVFAC (r2=0.349 p<0.001).
Figure 4: Relation between the change in CMRI-derived-RVEF and the change in echo parameters. The dotted lines represents the SD of the repeatability of CMRI-based-RVEF (ref: Bradlow) and the SD of interobserver variability of the four different echo- parameters. RVEF = right ventricular ejection fraction; RVFAC = right ventricular fractional area change. TAPSE = tricuspid annulus plane systolic excursion. FLWM = fractional longitudinal wall motion. FTWM = fractional transverse wall motion.
The sensitivity, specificity, NPV and PPV are summarized in table 4. Sensitivity of echo for predicting a deterioration in RV systolic function was poor for all four parameters, with the highest sensitivity for RVFAC (56%).
Chapter 5
83
5