Page 46 - Assessing right ventricular function and the pulmonary circulation in pulmonary hypertension Onno Anthonius Spruijt

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Figure 2: Atrial Size and Emptying Fractions. The figure depicts the different concepts related to RA volumes and the related concepts of total, passive, and RA emptying fractions. EV = emptying volume; RAEF = right atrial emptying fractions; Vmax = maximal volume; Vmin = minimal volume; VpreA = pre-atrial contraction volume.
CMR protocol in the validation cohort
CMR was performed on a 1.5T Sonato scanner (Siemens Medical Solutions, Erlangen, Germany), equipped with a 6-element phased-array receiver coil. Short-axis images from base to apex of the ventricles were obtained with a typical slice thickness of 5mm, and an interslice gap of 5mm was used for estimation of ventricular volumes using the Simpson method, as previously described [14]. The thresholds chosen for the CMR categorical classification were pre-defined at the beginning of the study. We chose the threshold of 35% for moderate RVEF dysfunction similar to the previously established cutoff in the study of van de Veerdonk et al. [14].
In addition, on the basis of a prior study from our group, we found that RVFAC of 25% corresponded best to an RVEF of 35% [15]. We used the same threshold for RA area for the echocardiographic and CMR studies.