Page 105 - Assessing right ventricular function and the pulmonary circulation in pulmonary hypertension Onno Anthonius Spruijt

A.
100
50
HR: DLCO<43% vs. DLCO 43-62%: 0.32 (95% CI: 0.14-0.76)* HR: DLCO<43% vs. DLCO>62%: 0.23 (95% CI: 0.09-0.58)*
DLCO<43% DLCO 43-62% DLCO >62%
Chapter 6
0
05101520
B.
100
50
Time (years)
HR: DLCO<43% vs. DLCO 43-62%: 0.23 (95% CI: 0.07-0.74) HR: DLCO<43% vs. DLCO>62%: 0.13 (95% CI: 0.04-0.45)
DLCO<43% DLCO 43-62% DLCO >62%
C.
100
50
Tim e (years)
HR: 0.58 (95% CI: 0.24-1.40) p= 0.226
DLCO<43%-noFUMRI DLCO<43%-FUMRI
0
05101520
0
05101520
Tim e (years)
Figure 5: Survival analyses. A: Difference in survival between the DLCO<42%, DLCO 43-62% and DLCO≥63% groups in the total cohort (n=166). The DLCO<42% group showed a worse survival than the moderately reduced DLCO and preserved DLCO groups. B: Difference in survival between the severely reduced DLCO group, the moderately reduced DLCO and preserved DLCO group in the cohort in which a CMRI at follow-up was available (n=68). Also in this selected cohort the DLCO<42% group showed a worse survival compared to other two groups. C: Difference in survival between the group with and without a CMRI at follow up in the DLCO<42% group (n=42). No difference in survival was found between the group with and without a CMRI at follow-up in the DLCO<42% group. * adjusted for age and left ventricular end diastolic volume index.
103
6
% survival % survival % survival