Page 107 - Risk quantification and modification in older patients with colorectal cancer

Physical performance and poor surgical outcomes Appendix A Baseline characteristics with stratification based on preoperative use of a mobility aid
Total number of patients (n)
Mean age (SD) Gender (%)
Male
Female BMIa kg/m2
BMI < 25
BMI ≥ 25 Comorbidity (%)
Cardiac Comorbidity
CCIb score ≥2 Tumour location (%)
Colon
Rectum Tumour stage (%)
I
II
III
ASA score (%) III or IV
(Neo)adjuvant treatment Neoadjuvant chemoradiation Adjuvant chemotherapy
Type of surgery Laparoscopic
Open
Functional parameters
ADL Dependency (Katz ≥2) Yes
No
Body composition
Mean Skeletal Muscle Massc (SD)
For men
For women
Mean Muscle Density (SD)d
For men
For women
All patients
174 78.0 5.1
89 (51) 85 (49)
79 (45) 95 (55)
9 (5) 70 (40)
143 (82) 31 (18)
50 (29) 66 (38) 58 (33)
48 (28)
9 (5) 28 (16)
114 (66) 60 (34)
9 (5) 165 (95)
Use of mobility aid
36
No use of
mobility aid p
136
77.5 (4.9) 0.01
72 (53) 0.36 64 (47)
68 (50) 0.02 68 (50)
19 (14) 0.02 49 (36) 0.02
109 (80) 0.2 27 (20)
39 (29) 0.7 50 (37)
47 (35)
33 (24) 0.04
9 (7) 0.4 35 (26) 0.06
92 (68) 0.3 44 (32)
3 (2) 0.001 133 (98)
43.6 (8.0) 0.3 35.5 (4.8) 0.2
44.1 (8.0) 46.3 35.9 (5.1) 37.2
28.9 (8.0) 24.9
25.8 (8.5) 23.0
(7.2)
(10.1)
index; bCCI, Charlson Comorbidity
80
16 20
10 26
11 21
32 4
11 15 10
15
0 2
21 15
6 30
(5.3)
(44) (56)
(28) (72)
(31) (58)
(89) (11)
(31) (42) (28)
(42)
(6)
(58) (42)
(17) (83)
(7.9) (6.2)
29.7 (7.9) 0.03 26.7 (7.8) 0.09
Mean with (SD) or frequency with percentage (%). aBMI, body mass Index;,cSkeletal Muscle Mass in cm2/m2. dMuscle Density in HU
105
5