Page 169 - scheppingen

MIR147B: A NOVEL KEY REGULATOR OF IL-1β-MEDIATED INFLAMMATION IN ASTROCYTES
Supplementary Table 2 Complete list of differentially expressed mRNAs as determined by mRNA-sequencing of control and IL-1β stimulated human astrocyte cultures.
Gene
Description
Location
Control FPKM
IL-1β FPKM
Log2(Fold Change)
p-value
Adjusted p-valuea
CCL20
C-C motif chemo- kine ligand 20
chr2:227813841- 227817564
0
51.2757
inf
5.00E-05
0.0124559
OAS2
2’-5’-oligoadenylate synthetase 2
chr12:112906776- 113017751
0.146736
13.1993
6.4911
0.00015
0.0310521
OAS1
2’-5’-oligoadenylate synthetase 1
chr12:112906776- 113017751
0.153149
25.2314
7.36414
5.00E-05
0.0124559
FCRLA
Fc receptor like A
chr1:161706971- 161714352
0.309749
1.20955
1.9653
0.00025
0.0453642
C3
complement C3
chr19:6677703- 6737603
0.310427
20.0424
6.01266
5.00E-05
0.0124559
APOL1
apolipoprotein L1
chr22:36253009- 36267530
0.384288
3.53226
3.20033
5.00E-05
0.0124559
MCTP1
multiple C2 and transmembrane domain contai- ning 1
chr5:94152965- 95284575
0.418875
1.89586
2.17826
5.00E-05
0.0124559
LUCAT1
lung cancer asso- ciated transcript 1 (non-protein coding)
chr5:91302030- 91314484
0.602348
6.1486
3.35159
5.00E-05
0.0124559
IFI44L
interferon induced protein 44 like
chr1:78619921- 78647788
0.798437
44.5501
5.80211
5.00E-05
0.0124559
BIRC3
baculoviral IAP repeat containing 3
chr11:102317449- 102339403
0.881077
21.8314
4.63099
5.00E-05
0.0124559
HERC6
HECT and RLD domain containing E3 ubiquitin pro- tein ligase family member 6
chr4:88378698- 88443111
0.948065
14.3077
3.91566
5.00E-05
0.0124559
IFIH1
interferon induced with helicase C domain 1
chr2:162267078- 162318703
1.08361
10.076
3.21699
0.00025
0.0453642
SLC7A2
solute carrier family 7 member 2
chr8:17494367- 17570573
1.1903
39.438
5.05018
5.00E-05
0.0124559
MX1
MX dynamin like GTPase 1
chr21:41420303- 41459214
1.20825
53.308
5.46336
5.00E-05
0.0124559
IL6
interleukin 6
chr7:22725394- 22732002
1.50528
236.633
7.29648
5.00E-05
0.0124559
OAS3
2’-5’-oligoadenylate synthetase 3
chr12:112906776- 113017751
1.54914
27.6823
4.15943
5.00E-05
0.0124559
RAB27B
RAB27B, member RAS oncogene family
chr18:54717859- 54898083
1.61661
7.16462
2.14792
0.00025
0.0453642
CHI3L2
chitinase 3 like 2
chr1:111186326- 111243440
1.63045
19.0502
3.54646
5.00E-05
0.0124559
DDX60
DExD/H-box heli- case 60
chr4:168216292- 168318807
1.70224
9.23533
2.43973
5.00E-05
0.0124559
167
six