Page 164 - Human Bile Acid Metabolism: a Postprandial Perspective
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Chapter 8
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75. Eggink HM, Soeters MR, Pols TW. TGR5 ligands as potential therapeutics in inflammatory diseases. Int J Interfer Cytokine Med Res 2014; 6: 27−38.
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79. Péan N, Doignon I, Garcin I, et al. The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice. Hepatology 2013; 58: 1451−60.
80. Lou G, Ma X, Fu X, et al. GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells. PLoS One 2014; 9: 1−10.
81. Haselow K, Bode JG, Wammers M, et al. Bile acids PKA-dependently induce a switch of the IL-10/ IL-12 ratio and reduce proinflammatory capability of human macrophages. J Leukoc Biol 2013; 94: 1253−64.
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85. Perino A, Pols TW, Nomura M, Stein S, Pellicciari R, Schoonjans K. TGR5 reduces macrophage migration through mTOR-induced C/EBPbeta differential translation. J Clin Invest 2014; 124: 5424−36.
86. Cipriani S, Mencarelli A, Chini MG, et al. The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis. PLoS One 2011; 6: e25637.
87. Yoneno K, Hisamatsu T, Shimamura K, et al. TGR5 signalling inhibits the production of pro- inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn’s disease. Immunology 2013; 139: 19−29.
88. Hov JR, Keitel V, Schrumpf E, Häussinger D, Karlsen TH. TGR5 sequence variation in primary sclerosing cholangitis. Dig Dis 2011; 29: 78−84.
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