Page 24 - Advanced echocardiography in characterization and management of patients with secondary mitral regurgitation

Chapter one. General introduction and outline of thesis
and define the most appropriate transcatheter therapy. In addition, advances in fusion imaging, where noninvasive three-dimensional imaging modalities can be overlaid on to fluoroscopy, facilitate the communication between imagers and interventionalists and procedural guidance.
Outline of this thesis
The objective of this thesis was to evaluate the role of advanced echocardiography for the risk stratification and treatment guidance of patients with secondary mitral regurgitation.
Part I describes epidemiological characteristics of patients with mitral regurgitation and how these effect treatment and outcome. Chapter 2 evaluates the sex differences in secondary mitral regurgitation and how it impacts outcome.
Part II focuses on the role of echocardiography and advanced echocardiography (speckle tracking) in defining predictors of outcome in patients with secondary mitral regurgitation. Chapter 3 evaluates the incremental prognostic value of LV GLS over LVEF in secondary mitral regurgitation. Chapter 4 has analyzed the ratio between mitral regurgitant volume and LV end-diastolic volume as a predictor of outcome in secondary mitral regurgitation. Chapter 5 evaluates geometrical mitral valve differences in patients with secondary mitral regurgitation treated with transcatheter mitral valve repair. Chapter 6 evaluates an echocardiographic marker for right ventricular-arterial coupling in patients with significant secondary mitral regurgitation and it association with outcome.
22